Population Pharmacokinetics and Use of Monte Carlo Simulation To Evaluate Currently Recommended Dosing Regimens of Ciprofloxacin in Adult Patients with Cystic Fibrosis

Pharmacodynamic data on ciprofloxacin indicate that a target area under the concentration-time curve from 0 to 24 h (AUC(0–24))/MIC ratio of ≥125 is necessary to achieve optimal bactericidal activity for the treatment of gram-negative pneumonia. The purpose of this prospective study was to (i) devel...

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Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Montgomery, Megan J., Beringer, Paul M., Aminimanizani, Amir, Louie, Stan G., Shapiro, Bertrand J., Jelliffe, Roger, Gill, Mark A.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2001
Предметы:	Pharmacology
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11709326/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.12.3468-3473.2001
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