Daptomycin Pharmacokinetics and Safety following Administration of Escalating Doses Once Daily to Healthy Subjects

The purpose of this paper is to establish the pharmacokinetics and safety of escalating, once-daily doses of daptomycin, a novel lipopeptide antibiotic active against gram-positive pathogens, including those resistant to methicillin and vancomycin. This phase 1, multiple-dose, double-blind study inv...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Dvorchik, Barry H., Brazier, David, DeBruin, Michael F., Arbeit, Robert D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.4.1318-1323.2003
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