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Population Pharmacokinetics and Use of Monte Carlo Simulation To Evaluate Currently Recommended Dosing Regimens of Ciprofloxacin in Adult Patients with Cystic Fibrosis
Pharmacodynamic data on ciprofloxacin indicate that a target area under the concentration-time curve from 0 to 24 h (AUC(0–24))/MIC ratio of ≥125 is necessary to achieve optimal bactericidal activity for the treatment of gram-negative pneumonia. The purpose of this prospective study was to (i) devel...
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主要な著者: | , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Microbiology
2001
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90855/ https://ncbi.nlm.nih.gov/pubmed/11709326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3468-3473.2001 |
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