Population Pharmacokinetics and Use of Monte Carlo Simulation To Evaluate Currently Recommended Dosing Regimens of Ciprofloxacin in Adult Patients with Cystic Fibrosis

Pharmacodynamic data on ciprofloxacin indicate that a target area under the concentration-time curve from 0 to 24 h (AUC(0–24))/MIC ratio of ≥125 is necessary to achieve optimal bactericidal activity for the treatment of gram-negative pneumonia. The purpose of this prospective study was to (i) devel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Montgomery, Megan J., Beringer, Paul M., Aminimanizani, Amir, Louie, Stan G., Shapiro, Bertrand J., Jelliffe, Roger, Gill, Mark A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2001
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC90855/
https://ncbi.nlm.nih.gov/pubmed/11709326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3468-3473.2001
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