Activation by 9-(R)-[2-(Phosphonomethoxy)Propyl]Adenine of Chemokine (RANTES, Macrophage Inflammatory Protein 1α) and Cytokine (Tumor Necrosis Factor Alpha, Interleukin-10 [IL-10], IL-1β) Production

Development of a novel group of antiviral agents, acyclic nucleoside phosphonates, has provided a new perspective for treating human immunodeficiency virus (HIV) infection. One of the compounds, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (PMPA) (tenofovir), has been shown to confer complete protectio...

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Bibliografiske detaljer
Main Authors: Zídek, Zdenĕk, Franková, Daniela, Holý, Antonín
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90841/
https://ncbi.nlm.nih.gov/pubmed/11709312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3381-3386.2001
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