Activity of 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine against Schistosomiasis mansoni in Mice

The activity of the acyclic nucleotide analogue 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine [(S)-HPMPA] against Schistosoma mansoni was investigated in mice. The compound was injected intraperitoneally, usually on two or five consecutive days, at 10 to 20 mg/kg of body weight/day. The treatm...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Botros, Sanaa, William, Samia, Hammam, Olfat, Zídek, Zden̆ek, Holý, Antonín
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Experimental Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638494/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3853-3858.2003
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