Pharmacokinetics and Bioavailability of the Anti-Human Immunodeficiency Virus Nucleotide Analog 9-[(R)2-(Phosphonomethoxy)Propyl]Adenine (PMPA) in Dogs

The pharmacokinetics, bioavailability, and metabolism of the anti-human immunodeficiency virus nucleotide analog 9[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) were determined in beagle dogs following intravenous, intraperitoneal, and oral administration. Fasted male beagle dogs (n = 5) were pretre...

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Main Authors: Cundy, Kenneth C., Sueoka, Cathy, Lynch, Geoffrey R., Griffin, Linda, Lee, William A., Shaw, Jeng-Pyng
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC105518/
https://ncbi.nlm.nih.gov/pubmed/9517952
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