9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques.

The long-term therapeutic and toxic effects of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) were evaluated in simian immunodeficiency virus (SIV)-infected newborn rhesus macaques. Four untreated SIV-infected newborn macaques developed persistently high levels of viremia, and three of the four animal...

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Main Authors: Van Rompay, K K, Cherrington, J M, Marthas, M L, Berardi, C J, Mulato, A S, Spinner, A, Tarara, R P, Canfield, D R, Telm, S, Bischofberger, N, Pedersen, N C
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC163581/
https://ncbi.nlm.nih.gov/pubmed/8913470
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