Pharmacokinetics and Bioavailability of the Anti-Human Immunodeficiency Virus Nucleotide Analog 9-[(R)2-(Phosphonomethoxy)Propyl]Adenine (PMPA) in Dogs

The pharmacokinetics, bioavailability, and metabolism of the anti-human immunodeficiency virus nucleotide analog 9[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) were determined in beagle dogs following intravenous, intraperitoneal, and oral administration. Fasted male beagle dogs (n = 5) were pretre...

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Εκδόθηκε σε:	Antimicrob Agents Chemother
Κύριοι συγγραφείς:	Cundy, Kenneth C., Sueoka, Cathy, Lynch, Geoffrey R., Griffin, Linda, Lee, William A., Shaw, Jeng-Pyng
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1998
Θέματα:	Pharmacology
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105518/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9517952/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.3.687
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