Activity of 9-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]Adenine against Schistosomiasis mansoni in Mice

The activity of the acyclic nucleotide analogue 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine [(S)-HPMPA] against Schistosoma mansoni was investigated in mice. The compound was injected intraperitoneally, usually on two or five consecutive days, at 10 to 20 mg/kg of body weight/day. The treatm...

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Bibliografiske detaljer
Main Authors: Botros, Sanaa, William, Samia, Hammam, Olfat, Zídek, Zden̆ek, Holý, Antonín
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296212/
https://ncbi.nlm.nih.gov/pubmed/14638494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.12.3853-3858.2003
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