Biological Effects of Short-Term or Prolonged Administration of 9-[2-(Phosphonomethoxy)Propyl]Adenine (Tenofovir) to Newborn and Infant Rhesus Macaques

The reverse transcriptase inhibitor 9-[2-(phosphonomethoxy)propyl]adenine (PMPA; tenofovir) was previously found to offer strong prophylactic and therapeutic benefits in an infant macaque model of pediatric human immunodeficiency virus (HIV) infection. We now summarize the toxicity and safety of PMP...

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Päätekijät: Van Rompay, Koen K. A., Brignolo, Laurie L., Meyer, Dennis J., Jerome, Christopher, Tarara, Ross, Spinner, Abigail, Hamilton, Marta, Hirst, Linda L., Bennett, David R., Canfield, Don R., Dearman, Trish G., Von Morgenland, Wilhelm, Allen, Phil C., Valverde, Celia, Castillo, Alesha B., Martin, R. Bruce, Samii, Valerie F., Bendele, Ray, Desjardins, John, Marthas, Marta L., Pedersen, Niels C., Bischofberger, Norbert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC400569/
https://ncbi.nlm.nih.gov/pubmed/15105094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1469-1487.2004
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