Biological Effects of Short-Term or Prolonged Administration of 9-[2-(Phosphonomethoxy)Propyl]Adenine (Tenofovir) to Newborn and Infant Rhesus Macaques

The reverse transcriptase inhibitor 9-[2-(phosphonomethoxy)propyl]adenine (PMPA; tenofovir) was previously found to offer strong prophylactic and therapeutic benefits in an infant macaque model of pediatric human immunodeficiency virus (HIV) infection. We now summarize the toxicity and safety of PMP...

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發表在:	Antimicrob Agents Chemother
Principais autores:	Van Rompay, Koen K. A., Brignolo, Laurie L., Meyer, Dennis J., Jerome, Christopher, Tarara, Ross, Spinner, Abigail, Hamilton, Marta, Hirst, Linda L., Bennett, David R., Canfield, Don R., Dearman, Trish G., Von Morgenland, Wilhelm, Allen, Phil C., Valverde, Celia, Castillo, Alesha B., Martin, R. Bruce, Samii, Valerie F., Bendele, Ray, Desjardins, John, Marthas, Marta L., Pedersen, Niels C., Bischofberger, Norbert
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2004
主題:	Antiviral Agents
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1469-1487.2004
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