Biological Effects of Short-Term or Prolonged Administration of 9-[2-(Phosphonomethoxy)Propyl]Adenine (Tenofovir) to Newborn and Infant Rhesus Macaques

The reverse transcriptase inhibitor 9-[2-(phosphonomethoxy)propyl]adenine (PMPA; tenofovir) was previously found to offer strong prophylactic and therapeutic benefits in an infant macaque model of pediatric human immunodeficiency virus (HIV) infection. We now summarize the toxicity and safety of PMP...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Van Rompay, Koen K. A., Brignolo, Laurie L., Meyer, Dennis J., Jerome, Christopher, Tarara, Ross, Spinner, Abigail, Hamilton, Marta, Hirst, Linda L., Bennett, David R., Canfield, Don R., Dearman, Trish G., Von Morgenland, Wilhelm, Allen, Phil C., Valverde, Celia, Castillo, Alesha B., Martin, R. Bruce, Samii, Valerie F., Bendele, Ray, Desjardins, John, Marthas, Marta L., Pedersen, Niels C., Bischofberger, Norbert
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Materias:	Antiviral Agents
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1469-1487.2004
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