Biological Effects of Short-Term or Prolonged Administration of 9-[2-(Phosphonomethoxy)Propyl]Adenine (Tenofovir) to Newborn and Infant Rhesus Macaques

The reverse transcriptase inhibitor 9-[2-(phosphonomethoxy)propyl]adenine (PMPA; tenofovir) was previously found to offer strong prophylactic and therapeutic benefits in an infant macaque model of pediatric human immunodeficiency virus (HIV) infection. We now summarize the toxicity and safety of PMP...

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Main Authors: Van Rompay, Koen K. A., Brignolo, Laurie L., Meyer, Dennis J., Jerome, Christopher, Tarara, Ross, Spinner, Abigail, Hamilton, Marta, Hirst, Linda L., Bennett, David R., Canfield, Don R., Dearman, Trish G., Von Morgenland, Wilhelm, Allen, Phil C., Valverde, Celia, Castillo, Alesha B., Martin, R. Bruce, Samii, Valerie F., Bendele, Ray, Desjardins, John, Marthas, Marta L., Pedersen, Niels C., Bischofberger, Norbert
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC400569/
https://ncbi.nlm.nih.gov/pubmed/15105094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1469-1487.2004
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