Development and Validation of Limited-Sampling Strategies for Predicting Amoxicillin Pharmacokinetic and Pharmacodynamic Parameters

Amoxicillin plasma concentrations (n = 1,152) obtained from 48 healthy subjects in two bioequivalence studies were used to develop limited-sampling strategy (LSS) models for estimating the area under the concentration-time curve (AUC), the maximum concentration of drug in plasma (C(max)), and the ti...

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Detalhes bibliográficos
Main Authors: Suarez-Kurtz, Guilherme, Ribeiro, Frederico Mota, Vicente, Flávio L., Struchiner, Claudio J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90778/
https://ncbi.nlm.nih.gov/pubmed/11600352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3029-3036.2001
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