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Pharmacokinetic and Pharmacodynamic Parameters for Antimicrobial Effects of Cefotaxime and Amoxicillin in an In Vitro Kinetic Model

An in vitro kinetic model was used to study the relation between pharmacokinetic and pharmacodynamic (PK-PD) parameters for antimicrobial effect, e.g., the time above MIC (T>MIC), maximum concentration in serum (C(max)), and area under the concentration-time curve (AUC). Streptococcus pyogenes an...

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Detalhes bibliográficos
Main Authors: Gustafsson, I., Löwdin, E., Odenholt, I., Cars, O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90674/
https://ncbi.nlm.nih.gov/pubmed/11502511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.9.2436-2440.2001
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