Pharmacokinetic and Pharmacodynamic Parameters for Antimicrobial Effects of Cefotaxime and Amoxicillin in an In Vitro Kinetic Model

An in vitro kinetic model was used to study the relation between pharmacokinetic and pharmacodynamic (PK-PD) parameters for antimicrobial effect, e.g., the time above MIC (T>MIC), maximum concentration in serum (C(max)), and area under the concentration-time curve (AUC). Streptococcus pyogenes and E...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Gustafsson, I., Löwdin, E., Odenholt, I., Cars, O.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Experimental Therapeutics
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11502511/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.9.2436-2440.2001
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