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Pharmacokinetic and Pharmacodynamic Parameters for Antimicrobial Effects of Cefotaxime and Amoxicillin in an In Vitro Kinetic Model

An in vitro kinetic model was used to study the relation between pharmacokinetic and pharmacodynamic (PK-PD) parameters for antimicrobial effect, e.g., the time above MIC (T>MIC), maximum concentration in serum (C(max)), and area under the concentration-time curve (AUC). Streptococcus pyogenes and E...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Gustafsson, I., Löwdin, E., Odenholt, I., Cars, O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11502511/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.9.2436-2440.2001
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