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Limited sampling strategy for determining metformin area under the plasma concentration–time curve
AIM: The aim was to develop and validate limited sampling strategy (LSS) models to predict the area under the plasma concentration–time curve (AUC) for metformin. METHODS: Metformin plasma concentrations (n = 627) at 0–24 h after a single 500 mg dose were used for LSS development, based on all subse...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137825/ https://ncbi.nlm.nih.gov/pubmed/27324407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13049 |
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