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Limited-Sampling Strategy Models for Itraconazole and Hydroxy-Itraconazole Based on Data from a Bioequivalence Study

The extensive interindividual variability in oral bioavailability of itraconazole prompted an assessment of the bioequivalence of two formulations marketed in Brazil, namely, Sporanox (reference) and Traconal (test). Eighteen healthy volunteers received single 200-mg oral doses of each formulation a...

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Detalhes bibliográficos
Main Authors: Suarez-Kurtz, Guilherme, Bozza, Fernando A., Vicente, Flavio L., Ponte, Cristiano G., Struchiner, Claudio J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89033/
https://ncbi.nlm.nih.gov/pubmed/9869578
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