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Limited-Sampling Strategy Models for Itraconazole and Hydroxy-Itraconazole Based on Data from a Bioequivalence Study

The extensive interindividual variability in oral bioavailability of itraconazole prompted an assessment of the bioequivalence of two formulations marketed in Brazil, namely, Sporanox (reference) and Traconal (test). Eighteen healthy volunteers received single 200-mg oral doses of each formulation a...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Suarez-Kurtz, Guilherme, Bozza, Fernando A., Vicente, Flavio L., Ponte, Cristiano G., Struchiner, Claudio J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89033/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869578/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.1.134
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