Pharmacokinetics and Pharmacodynamics of Amoxicillin-Sulbactam, a Novel Aminopenicillin–β-Lactamase Inhibitor Combination, against Escherichia coli

We evaluated the pharmacokinetics of amoxicillin-sulbactam (AMX-SUL), a novel drug combination, and its pharmacodynamics against Escherichia coli in 12 volunteers receiving a single oral dose (1,000 mg). Peak serum bactericidal and urine inhibitory activities in most volunteers were observed against...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bantar, Carlos, Nicola, Federico, Arenoso, Hector J., Galas, Marcelo, Soria, Liliana, Dana, Diego, Rossi, Alicia, Bianchini, Hebe, Jasovich, Abel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89308/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10348782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.6.1503
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