Pharmacokinetics and Pharmacodynamics of Amoxicillin-Sulbactam, a Novel Aminopenicillin–β-Lactamase Inhibitor Combination, against Escherichia coli

We evaluated the pharmacokinetics of amoxicillin-sulbactam (AMX-SUL), a novel drug combination, and its pharmacodynamics against Escherichia coli in 12 volunteers receiving a single oral dose (1,000 mg). Peak serum bactericidal and urine inhibitory activities in most volunteers were observed against...

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Main Authors: Bantar, Carlos, Nicola, Federico, Arenoso, Hector J., Galas, Marcelo, Soria, Liliana, Dana, Diego, Rossi, Alicia, Bianchini, Hebe, Jasovich, Abel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89308/
https://ncbi.nlm.nih.gov/pubmed/10348782
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