Selection and Genetic Characterization of Streptococcus pneumoniae Mutants Resistant to the Des-F(6) Quinolone BMS-284756

Existing quinolones are known to target the type II topoisomerases in bacteria. In order to determine which of these targets are of key importance in Streptococcus pneumoniae treated with BMS-284756 (T-3811ME), a novel des-F(6) quinolone, resistant mutants were selected in several steps of increasin...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Hartman-Neumann, Sandra, DenBleyker, Kenneth, Pelosi, Lenore A., Lawrence, Laura E., Barrett, John F., Dougherty, Thomas J.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2001
Matèries:	Mechanisms of Resistance
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2865-2870.2001
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