Selection and Genetic Characterization of Streptococcus pneumoniae Mutants Resistant to the Des-F(6) Quinolone BMS-284756

Existing quinolones are known to target the type II topoisomerases in bacteria. In order to determine which of these targets are of key importance in Streptococcus pneumoniae treated with BMS-284756 (T-3811ME), a novel des-F(6) quinolone, resistant mutants were selected in several steps of increasin...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Hartman-Neumann, Sandra, DenBleyker, Kenneth, Pelosi, Lenore A., Lawrence, Laura E., Barrett, John F., Dougherty, Thomas J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2865-2870.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!