Selection and Genetic Characterization of Streptococcus pneumoniae Mutants Resistant to the Des-F(6) Quinolone BMS-284756

Existing quinolones are known to target the type II topoisomerases in bacteria. In order to determine which of these targets are of key importance in Streptococcus pneumoniae treated with BMS-284756 (T-3811ME), a novel des-F(6) quinolone, resistant mutants were selected in several steps of increasin...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	Hartman-Neumann, Sandra, DenBleyker, Kenneth, Pelosi, Lenore A., Lawrence, Laura E., Barrett, John F., Dougherty, Thomas J.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2001
Aiheet:	Mechanisms of Resistance
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2865-2870.2001
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