Selection and Genetic Characterization of Streptococcus pneumoniae Mutants Resistant to the Des-F(6) Quinolone BMS-284756

Existing quinolones are known to target the type II topoisomerases in bacteria. In order to determine which of these targets are of key importance in Streptococcus pneumoniae treated with BMS-284756 (T-3811ME), a novel des-F(6) quinolone, resistant mutants were selected in several steps of increasin...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Hartman-Neumann, Sandra, DenBleyker, Kenneth, Pelosi, Lenore A., Lawrence, Laura E., Barrett, John F., Dougherty, Thomas J.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2001
Gaiak:	Mechanisms of Resistance
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2865-2870.2001
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