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Mutant Prevention Concentration of Garenoxacin (BMS-284756) for Ciprofloxacin-Susceptible or -Resistant Staphylococcus aureus

The new quinolone garenoxacin (BMS-284756), which lacks a C-6 fluorine, was examined for its ability to block the growth of Staphylococcus aureus. Measurement of the MIC and the mutant prevention concentration (MPC) revealed that garenoxacin was 20-fold more potent than ciprofloxacin for a variety o...

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Autors principals: Zhao, Xilin, Eisner, William, Perl-Rosenthal, Nathan, Kreiswirth, Barry, Drlica, Karl
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149307/
https://ncbi.nlm.nih.gov/pubmed/12604537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.1023-1027.2003
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