Mutant Prevention Concentration of Garenoxacin (BMS-284756) for Ciprofloxacin-Susceptible or -Resistant Staphylococcus aureus

The new quinolone garenoxacin (BMS-284756), which lacks a C-6 fluorine, was examined for its ability to block the growth of Staphylococcus aureus. Measurement of the MIC and the mutant prevention concentration (MPC) revealed that garenoxacin was 20-fold more potent than ciprofloxacin for a variety o...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Zhao, Xilin, Eisner, William, Perl-Rosenthal, Nathan, Kreiswirth, Barry, Drlica, Karl
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149307/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604537/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.3.1023-1027.2003
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