In Vivo Monitoring of Intracellular ATP Levels in Leishmania donovani Promastigotes as a Rapid Method To Screen Drugs Targeting Bioenergetic Metabolism

A method for the rapid screening of drugs targeting the bioenergetic metabolism of Leishmania spp. was developed. The system is based on the monitoring of changes in the intracellular ATP levels of Leishmania donovani promastigotes that occur in vivo, as assessed by the luminescence produced by para...

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Bibliografiske detaljer
Main Authors: Luque-Ortega, Juan Román, Rivero-Lezcano, Octavio Miguel, Croft, Simon L., Rivas, Luis
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90434/
https://ncbi.nlm.nih.gov/pubmed/11257025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1121-1125.2001
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