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In Vivo Monitoring of Intracellular ATP Levels in Leishmania donovani Promastigotes as a Rapid Method To Screen Drugs Targeting Bioenergetic Metabolism

A method for the rapid screening of drugs targeting the bioenergetic metabolism of Leishmania spp. was developed. The system is based on the monitoring of changes in the intracellular ATP levels of Leishmania donovani promastigotes that occur in vivo, as assessed by the luminescence produced by para...

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Hlavní autoři: Luque-Ortega, Juan Román, Rivero-Lezcano, Octavio Miguel, Croft, Simon L., Rivas, Luis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90434/
https://ncbi.nlm.nih.gov/pubmed/11257025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1121-1125.2001
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