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Miltefosine (Hexadecylphosphocholine) Inhibits Cytochrome c Oxidase in Leishmania donovani Promastigotes

Miltefosine (hexadecylphosphocholine [HePC]) is currently on trial as a first-choice, orally active drug for the treatment of visceral leishmaniasis when resistance to organic pentavalent antimonials becomes epidemic. However, data on the targets involved in its leishmanicidal mechanism have, until...

詳細記述

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書誌詳細
主要な著者: Luque-Ortega, Juan Román, Rivas, Luis
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855476/
https://ncbi.nlm.nih.gov/pubmed/17283192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01415-06
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