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Miltefosine (Hexadecylphosphocholine) Inhibits Cytochrome c Oxidase in Leishmania donovani Promastigotes
Miltefosine (hexadecylphosphocholine [HePC]) is currently on trial as a first-choice, orally active drug for the treatment of visceral leishmaniasis when resistance to organic pentavalent antimonials becomes epidemic. However, data on the targets involved in its leishmanicidal mechanism have, until...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855476/ https://ncbi.nlm.nih.gov/pubmed/17283192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01415-06 |
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