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Miltefosine (Hexadecylphosphocholine) Inhibits Cytochrome c Oxidase in Leishmania donovani Promastigotes

Miltefosine (hexadecylphosphocholine [HePC]) is currently on trial as a first-choice, orally active drug for the treatment of visceral leishmaniasis when resistance to organic pentavalent antimonials becomes epidemic. However, data on the targets involved in its leishmanicidal mechanism have, until...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Luque-Ortega, Juan Román, Rivas, Luis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855476/
https://ncbi.nlm.nih.gov/pubmed/17283192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01415-06
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