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Miltefosine (Hexadecylphosphocholine) Inhibits Cytochrome c Oxidase in Leishmania donovani Promastigotes

Miltefosine (hexadecylphosphocholine [HePC]) is currently on trial as a first-choice, orally active drug for the treatment of visceral leishmaniasis when resistance to organic pentavalent antimonials becomes epidemic. However, data on the targets involved in its leishmanicidal mechanism have, until...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Luque-Ortega, Juan Román, Rivas, Luis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855476/
https://ncbi.nlm.nih.gov/pubmed/17283192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01415-06
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