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Miltefosine Affects Lipid Metabolism in Leishmania donovani Promastigotes

Miltefosine (hexadecylphosphocholine [HePC]) is the first orally active antileishmanial drug. Transient HePC treatment of Leishmania donovani promastigotes at 10 μM significantly reduced the phosphatidylcholine content and enhanced the phosphatidylethanolamine (PE) content in parasite membranes, sug...

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Autors principals: Rakotomanga, M., Blanc, S., Gaudin, K., Chaminade, P., Loiseau, P. M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855451/
https://ncbi.nlm.nih.gov/pubmed/17242145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01123-06
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