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Miltefosine Affects Lipid Metabolism in Leishmania donovani Promastigotes
Miltefosine (hexadecylphosphocholine [HePC]) is the first orally active antileishmanial drug. Transient HePC treatment of Leishmania donovani promastigotes at 10 μM significantly reduced the phosphatidylcholine content and enhanced the phosphatidylethanolamine (PE) content in parasite membranes, sug...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855451/ https://ncbi.nlm.nih.gov/pubmed/17242145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01123-06 |
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