In Vivo Effect of α(1)-Acid Glycoprotein on Pharmacokinetics of Amprenavir, a Human Immunodeficiency Virus Protease Inhibitor

Observations from early clinical pharmacology studies of amprenavir, an inhibitor of human immunodeficiency virus type 1 (HIV-1) protease that is highly bound to human plasma proteins (∼90%), showed the single-dose pharmacokinetics of amprenavir to be variable between and within individuals. A cross...

Description complète

Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Sadler, Brian M., Gillotin, Catherine, Lou, Yu, Stein, Daniel S.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Pharmacology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.852-856.2001
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!