Pharmacokinetic and Pharmacodynamic Study of the Human Immunodeficiency Virus Protease Inhibitor Amprenavir after Multiple Oral Dosing

In a dose-ranging study of amprenavir (formerly 141W94), an inhibitor of the protease enzyme of human immunodeficiency virus (HIV) type 1, single-dose and steady-state pharmacokinetic parameters were estimated from plasma samples collected on day 1 and during week 3, respectively. Amprenavir was adm...

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Bibliographische Detailangaben
Hauptverfasser: Sadler, Brian M., Gillotin, Catherine, Lou, Yu, Stein, Daniel S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90235/
https://ncbi.nlm.nih.gov/pubmed/11120940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.30-37.2001
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