Pharmacokinetic and Pharmacodynamic Study of the Human Immunodeficiency Virus Protease Inhibitor Amprenavir after Multiple Oral Dosing

In a dose-ranging study of amprenavir (formerly 141W94), an inhibitor of the protease enzyme of human immunodeficiency virus (HIV) type 1, single-dose and steady-state pharmacokinetic parameters were estimated from plasma samples collected on day 1 and during week 3, respectively. Amprenavir was adm...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Sadler, Brian M., Gillotin, Catherine, Lou, Yu, Stein, Daniel S.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2001
Témata:	Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.30-37.2001
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