Bioavailability and Preliminary Clinical Efficacy of Intrarectal Artesunate in Ghanaian Children with Moderate Malaria

We report the first detailed pharmacokinetic assessment of intrarectal (i.r.) artesunate (ARS) in African children. Artesunate was given intravenously (i.v.; 2.4 mg/kg of body weight) and i.r. (10 or 20 mg/kg formulated as 50- or 200-mg suppositories [Rectocaps]) in a crossover study design to 34 Gh...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Krishna, Sanjeev, Planche, Tim, Agbenyega, Tsiri, Woodrow, Charles, Agranoff, Dan, Bedu-Addo, George, Owusu-Ofori, Alex K., Appiah, John Adabie, Ramanathan, Surash, Mansor, Sharif M., Navaratnam, Visweswaran
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2001
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90320/
https://ncbi.nlm.nih.gov/pubmed/11158748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.2.509-516.2001
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items