Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

Chemical mutagenesis of Staphylococcus aureus RN450 generated two strains that displayed a stable reduction (30- to 60-fold) in susceptibility to evernimicin. Cell-free translation reactions demonstrated that the resistance determinant was located in the ribosomal fraction. Compared to ribosomes iso...

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Hlavní autoři: McNicholas, Paul M., Mann, Paul A., Najarian, David J., Miesel, Lynn, Hare, Roberta S., Black, Todd A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90243/
https://ncbi.nlm.nih.gov/pubmed/11120948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.79-83.2001
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