In Vitro Uptake of SCH 27899 (Evernimicin) by Rat Alveolar Macrophages

The in vitro uptake of [(14)C]evernimicin ([(14)C]SCH 27899) by primary cultures of rat alveolar macrophages and hepatocytes was determined. Both cell populations exhibited linear rates of uptake. However, the initial rate of drug uptake by alveolar macrophages was about threefold higher than that b...

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Bibliografiske detaljer
Main Authors: Zbaida, Shmuel, Brieland, Joan, Krieter, Philip, Loebenberg, David, Krishna, Gopal, Horne, Debra, Lu, Xiaowen, Yuan, Yuan, Hare, Roberta, Cayen, Mitchell N., Patrick, James E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90404/
https://ncbi.nlm.nih.gov/pubmed/11181391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.959-961.2001
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