In Vitro Uptake of SCH 27899 (Evernimicin) by Rat Alveolar Macrophages

The in vitro uptake of [(14)C]evernimicin ([(14)C]SCH 27899) by primary cultures of rat alveolar macrophages and hepatocytes was determined. Both cell populations exhibited linear rates of uptake. However, the initial rate of drug uptake by alveolar macrophages was about threefold higher than that b...

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Detalhes bibliográficos
Main Authors: Zbaida, Shmuel, Brieland, Joan, Krieter, Philip, Loebenberg, David, Krishna, Gopal, Horne, Debra, Lu, Xiaowen, Yuan, Yuan, Hare, Roberta, Cayen, Mitchell N., Patrick, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90404/
https://ncbi.nlm.nih.gov/pubmed/11181391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.959-961.2001
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