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Efficacy of an Evernimicin (SCH27899) In Vitro and in an Animal Model of Lyme Disease

The MICs of evernimicin at which 90% of Borrelia burgdorferi patient isolates were inhibited ranged from 0.1 to 0.5 μg/ml. Evernimicin was as effective as ceftriaxone against B. burgdorferi in a murine model of experimental Lyme disease. As assessed by culturing the urinary bladders of infected C3H...

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Hlavní autoři: Pavia, Charles S., Wormser, Gary P., Nowakowski, John, Cacciapuoti, Anthony
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90397/
https://ncbi.nlm.nih.gov/pubmed/11181384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.936-937.2001
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