Efficacy of an Evernimicin (SCH27899) In Vitro and in an Animal Model of Lyme Disease

The MICs of evernimicin at which 90% of Borrelia burgdorferi patient isolates were inhibited ranged from 0.1 to 0.5 μg/ml. Evernimicin was as effective as ceftriaxone against B. burgdorferi in a murine model of experimental Lyme disease. As assessed by culturing the urinary bladders of infected C3H...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Pavia, Charles S., Wormser, Gary P., Nowakowski, John, Cacciapuoti, Anthony
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90397/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181384/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.3.936-937.2001
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