In Vitro Uptake of SCH 27899 (Evernimicin) by Rat Alveolar Macrophages

The in vitro uptake of [(14)C]evernimicin ([(14)C]SCH 27899) by primary cultures of rat alveolar macrophages and hepatocytes was determined. Both cell populations exhibited linear rates of uptake. However, the initial rate of drug uptake by alveolar macrophages was about threefold higher than that b...

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Hlavní autoři: Zbaida, Shmuel, Brieland, Joan, Krieter, Philip, Loebenberg, David, Krishna, Gopal, Horne, Debra, Lu, Xiaowen, Yuan, Yuan, Hare, Roberta, Cayen, Mitchell N., Patrick, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90404/
https://ncbi.nlm.nih.gov/pubmed/11181391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.959-961.2001
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