Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

Chemical mutagenesis of Staphylococcus aureus RN450 generated two strains that displayed a stable reduction (30- to 60-fold) in susceptibility to evernimicin. Cell-free translation reactions demonstrated that the resistance determinant was located in the ribosomal fraction. Compared to ribosomes iso...

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Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	McNicholas, Paul M., Mann, Paul A., Najarian, David J., Miesel, Lynn, Hare, Roberta S., Black, Todd A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.79-83.2001
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