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Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

Chemical mutagenesis of Staphylococcus aureus RN450 generated two strains that displayed a stable reduction (30- to 60-fold) in susceptibility to evernimicin. Cell-free translation reactions demonstrated that the resistance determinant was located in the ribosomal fraction. Compared to ribosomes iso...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: McNicholas, Paul M., Mann, Paul A., Najarian, David J., Miesel, Lynn, Hare, Roberta S., Black, Todd A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90243/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120948/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.79-83.2001
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