Influence of Human Sera on the In Vitro Activity of the Echinocandin Caspofungin (MK-0991) against Aspergillus fumigatus

There have been several reports that the activity of echinocandin antifungal agents is not affected or decreased in the presence of human sera. It is known that these drugs are bound >80% in animal and human sera. The activity of the echinocandin caspofungin (MK-0991), a 1,3-β-d-glucan synthase inhi...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Chiller, Tom, Farrokhshad, Kouros, Brummer, Elmer, Stevens, David A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Susceptibility
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3302-3305.2000
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