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Influence of Human Sera on the In Vitro Activity of the Echinocandin Caspofungin (MK-0991) against Aspergillus fumigatus

There have been several reports that the activity of echinocandin antifungal agents is not affected or decreased in the presence of human sera. It is known that these drugs are bound >80% in animal and human sera. The activity of the echinocandin caspofungin (MK-0991), a 1,3-β-d-glucan synthase inhi...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Chiller, Tom, Farrokhshad, Kouros, Brummer, Elmer, Stevens, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083631/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3302-3305.2000
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