Influence of Human Sera on the In Vitro Activity of the Echinocandin Caspofungin (MK-0991) against Aspergillus fumigatus

There have been several reports that the activity of echinocandin antifungal agents is not affected or decreased in the presence of human sera. It is known that these drugs are bound >80% in animal and human sera. The activity of the echinocandin caspofungin (MK-0991), a 1,3-β-d-glucan synthase inhi...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Chiller, Tom, Farrokhshad, Kouros, Brummer, Elmer, Stevens, David A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Susceptibility
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3302-3305.2000
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