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Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Acyclovir triphosphate is a potent inhibitor of hepatitis B virus DNA polymerase, but acyclovir treatment provides no benefit in patients with hepatitis B virus infection. This is due in part to the fact that hepatitis B virus, unlike herpes simplex virus, does not code for a viral thymidine kinase...

Celý popis

Uloženo v:
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Hostetler, Karl Y., Beadle, James R., Hornbuckle, William E., Bellezza, Christine A., Tochkov, Ilia A., Cote, Paul J., Gerin, John L., Korba, Brent E., Tennant, Bud C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2000
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.7.1964-1969.2000
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