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Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Acyclovir triphosphate is a potent inhibitor of hepatitis B virus DNA polymerase, but acyclovir treatment provides no benefit in patients with hepatitis B virus infection. This is due in part to the fact that hepatitis B virus, unlike herpes simplex virus, does not code for a viral thymidine kinase...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Hostetler, Karl Y., Beadle, James R., Hornbuckle, William E., Bellezza, Christine A., Tochkov, Ilia A., Cote, Paul J., Gerin, John L., Korba, Brent E., Tennant, Bud C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.7.1964-1969.2000
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