Antiviral Activities of Oral 1-O-Hexadecylpropanediol-3-Phosphoacyclovir and Acyclovir in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

Acyclovir triphosphate is a potent inhibitor of hepatitis B virus DNA polymerase, but acyclovir treatment provides no benefit in patients with hepatitis B virus infection. This is due in part to the fact that hepatitis B virus, unlike herpes simplex virus, does not code for a viral thymidine kinase...

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Main Authors: Hostetler, Karl Y., Beadle, James R., Hornbuckle, William E., Bellezza, Christine A., Tochkov, Ilia A., Cote, Paul J., Gerin, John L., Korba, Brent E., Tennant, Bud C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89993/
https://ncbi.nlm.nih.gov/pubmed/10858362
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