Immunization with Surface Antigen Vaccine Alone and after Treatment with 1-(2-Fluoro-5-Methyl-β-l-Arabinofuranosyl)-Uracil (l-FMAU) Breaks Humoral and Cell-Mediated Immune Tolerance in Chronic Woodchuck Hepatitis Virus Infection

Woodchucks chronically infected with the woodchuck hepatitis virus (WHV) were treated with the antiviral drug 1-(2-fluoro-5-methyl-β-l-arabinofuranosyl)-uracil (l-FMAU) or placebo for 32 weeks. Half the woodchucks in each group then received four injections of surface antigen vaccine during the next...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Menne, Stephan, Roneker, Carol A., Korba, Brent E., Gerin, John L., Tennant, Bud C., Cote, Paul J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2002
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC137055/
https://ncbi.nlm.nih.gov/pubmed/11991959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.11.5305-5314.2002
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