Immunization with Surface Antigen Vaccine Alone and after Treatment with 1-(2-Fluoro-5-Methyl-β-l-Arabinofuranosyl)-Uracil (l-FMAU) Breaks Humoral and Cell-Mediated Immune Tolerance in Chronic Woodchuck Hepatitis Virus Infection

Woodchucks chronically infected with the woodchuck hepatitis virus (WHV) were treated with the antiviral drug 1-(2-fluoro-5-methyl-β-l-arabinofuranosyl)-uracil (l-FMAU) or placebo for 32 weeks. Half the woodchucks in each group then received four injections of surface antigen vaccine during the next...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Menne, Stephan, Roneker, Carol A., Korba, Brent E., Gerin, John L., Tennant, Bud C., Cote, Paul J.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Vaccines and Antiviral Agents
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137055/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11991959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.11.5305-5314.2002
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